To achieve this, the team generated over 7,000 variations of Protegrin-1 through a high-throughput method, allowing them to quickly identify which modifications could enhance safety. They then used the LLM to evaluate these variations for their ability to selectively target bacterial membranes, effectively kill bacteria, and avoid harming human red blood cells. This AI-guided approach led to the creation of a refined version known as bacterially selective Protegrin-1.2 (bsPG-1.2).

In preliminary animal trials, mice treated with bsPG-1.2 and infected with multidrug-resistant bacteria showed a significant reduction in bacterial levels in their organs within six hours. These promising results suggest that bsPG-1.2 could potentially advance to human trials.

Seoul: Samsung Electronics said on Wednesday its second quarter (Q2) operating profit surged more than 15 times from a year earlier on the robust performance of its semiconductor business.

The world’s largest mobile phone and memory chip maker’s operating profit reached 10.44 trillion won ($7.54 billion) in the April-June period, compared with 668.5 billion won a year ago, the company said in a regulatory filing.

It is the first time that Samsung Electronics posted an operating profit of more than 10 trillion won in seven quarters since the third quarter of 2022. Its sales jumped 23.4 per cent on-year to 74.06 trillion won and net profit soared 471 percent to 9.84 trillion won.